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Pan-RAS-IN-1

Product Specifications

CAS Number

1835283-94-7

SKU

C01512-5mg

Target

Ras

Applications

Apoptosis

Smiles

NC1 (CCNCC1) C (=O) NCCC[N]2C=C (C3=CC=C (OC (F) (F) F) C=C3) C4=C2C=CC (=C4) CN5CCN (CC5) CC6=C (Cl) C=CC=C6Cl

Additionnal Information

Pan-RAS-IN-1, a pan-Ras inhibitor, binds to KRasG12D-GppNHp with a Kd less than 20 μM in MST, ITC and NMR assays, also binds to Ras proteins and exhibits lethality in cells partially dependent on expression of Ras proteins.

Storage Conditions

3 years -20°C powder

Available Sizes

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