HS-276
Product Specifications
CAS Number
2767422-72-8
SKU
C01511-5mg
Target
TAK1
Applications
MAPK
Smiles
CCC[N]1C (=NC2=CC=C (CN3CCCCC3) C=C12) NC (=O) C4=CC=CC (=C4) C (N) =O
Additionnal Information
HS-276, a potent and highly selective orally bioavailable transforming growth factor-β activated kinase-1 (TAK1) inhibitor with the Ki and IC50 of 2.5 nM and 2.3 nM respectively, shows significant inhibition of TNF-mediated cytokine profiles, correlating with significant attenuation of arthritic-like symptoms in the collagen-induced arthritis (CIA) mouse model of inflammatory rheumatoid arthritis (RA) .
Storage Conditions
3 years -20°C powder
Available Sizes
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
GTR15080789 1 Vial
Lentiviral human BEX5 shRNA (UAS) - Lentiviral human BEX5 shRNA (UAS) (25)
Sign In for Pricing
View Details 
orb3113478 100 µg
Cathepsin L/MEP/Ctsl Rabbit Polyclonal Antibody (Fluoro550)
Sign In for Pricing
View Details TL306976V 500 µL Each
Cytokeratin 2 (KRT76) Human shRNA Lentiviral Particle (Locus ID 51350)
Sign In for Pricing
View Details