GA-017
Product Specifications
CAS Number
2351906-74-4
SKU
C01502-5mg
Target
LATS
Applications
Hippo
Smiles
CC\C (=N\NC (=O) NCC1=CC (=CC=C1) O) C2=C (O) C (=C (O) C=C2) C
Additionnal Information
GA-017 inhibits the serine/threonine protein kinases large tumor suppressor kinase 1/2 (LATS1/2), which exerts inhibitory with IC50s against LATS1 and 2 of 4.10±0.79 and 3.92±0.42 nM, respectively, and competitively inhibits LATS1 and 2 against ATP, with Ki (inhibition constant) values of 0.58±0.11 and 0.25±0.03 nM, respectively.
Storage Conditions
3 years -20°C powder
Available Sizes
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