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AACOCF3

Product Specifications

CAS Number

149301-79-1

Synonyms

Arachidonyl trifluoromethyl keton

SKU

C01483-5mg

Target

Phospholipase (e.g. PLA)

Applications

Metabolism

Additionnal Information

AACOCF3 (Arachidonyl trifluoromethyl ketone) is an inhibitor of cytosolic phospholipase A2 (cPLA2) and calcium-independent phospholipase A2 (iPLA2) with IC50 of 1.5 μM and 6.0 μM, respectively. It inhibits aortic osteoinductive signalling and vascular calcification in the cholecalciferol-overload mouse model.

Storage Conditions

2 years -20°C liquid

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