GSK215
Product Specifications
CAS Number
2743427-26-9
SKU
C01481-5mg
Target
FAK
Applications
Protein Tyrosine Kinase
Smiles
CNC (=O) C1=C (NC2=CC (=NC=C2C (F) (F) F) NC3=C (OC) C=C (C=C3) N4CCN (CC4) CC (=O) NC (C (=O) N5CC (O) CC5C (=O) NC (C) C6=CC=C (C=C6) C7=C (C) N=CS7) C (C) (C) C) C=CC=C1
Additionnal Information
GSK215 is a potent and selective PROTAC focal adhesion kinase (FAK) degrader, which exerts FAK degradation in A549 non-small-cell lung cancer cells with DC50 of 1.3 nM by a strong time-dependence way and maximal degradation (Dmax) near the limit of the assay quantification (Dmax 99%) .
Storage Conditions
3 years -20°C powder
Available Sizes
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