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Aminopterin

Product Specifications

CAS Number

54-62-6

Synonyms

4-amino Folic Acid, 4-amino PGA, 4-Aminofolic acid, 4-Aminopteroylglutamic acid, Aminopteroylglutamic acid, APGA, NSC 739

SKU

C01423-5mg

Target

DHFR

Applications

Cell Cycle

Smiles

NC1=NC (=C2N=C (CNC3=CC=C (C=C3) C (=O) NC (CCC (O) =O) C (O) =O) C=NC2=N1) N

Additionnal Information

Aminopterin (4-amino Folic Acid, 4-amino PGA, 4-Aminofolic acid, 4-Aminopteroylglutamic acid, Aminopteroylglutamic acid, APGA, NSC 739), a folic acid antagonist, is a competitive inhibitor of dihydrofolate reductase (DHFR) with Ki of 3.7 pM.

Storage Conditions

3 years -20°C powder

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