Chiauranib

Product Specifications

CAS Number

1256349-48-0

Synonyms

CS2164

SKU

C01311-5mg

Target

CSF-1R

Applications

Protein Tyrosine Kinase

Smiles

COC1=CC2=C (C=C1) C (=CC=N2) OC3=CC4=C (C=C3) C (=CC=C4) C (=O) NC5=C (N) C=CC=C5

Additionnal Information

Chiauranib (CS2164) selectively inhibits multiple kinase targets aurora B kinase (AURKB), colony-stimulating factor 1 receptor (CSF1R), and vascular endothelial growth factor receptor (VEGFR) /platelet-derived growth factor receptor (PDGFR) /c-Kit , thereby inhibiting the rapid proliferation of tumor cells, enhancing the antitumor immunity, and inhibiting tumor angiogenesis, to achieve the anti-tumor efficacy.