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R59949

Product Specifications

CAS Number

120166-69-0

SKU

C01059-5mg

Target

Others

Applications

Others

Smiles

FC1=CC=C (C=C1) C (=C2CCN (CCN3C (=S) NC4=CC=CC=C4C3=O) CC2) C5=CC=C (F) C=C5

Additionnal Information

R59949, a diacylglycerol kinase (DGK) inhibitor with an IC50 of 300 nM, inhibits inducible nitric oxide production through decreasing transplasmalemmal L-arginine uptake in vascular smooth muscle cells. R59949 strongly inhibits type I DGK a and γ, and moderately attenuates type II DGK θ and κ.

Storage Conditions

3 years -20°C powder

Available Sizes

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