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Tolebrutinib

Product Specifications

CAS Number

1971920-73-6

Synonyms

SAR442168, PRN2246

SKU

C01038-5mg

Target

BTK

Applications

Protein Tyrosine Kinase

Smiles

NC1=NC=CC2=C1N (C (=O) N2C3CCCN (C3) C (=O) C=C) C4=CC=C (OC5=CC=CC=C5) C=C4

Additionnal Information

Tolebrutinib is an oral, CNS-penetrant, irreversible inhibitor of Bruton's tyrosine kinase (BTK) with IC50s of 0.4 nM and 0.7 nM in Ramos B cells and in HMC microglia cells, respectively.

Storage Conditions

3 years -20°C powder

Available Sizes

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