Serclutamab talirine

Product Specifications

CAS Number

2140174-56-5

Synonyms

ABBV-321, Anti-Egfr/pbd antibody-drug conjugate ABBV-321

SKU

C00981-1mg

Target

EGFR

Applications

Protein Tyrosine Kinase

Additionnal Information

Serclutamab Talirine (ABBV-321), is an antibody-drug conjugate (ADC) composed of an humanized immunoglobulin G1 anti-EGFR monoclonal antibody conjugated to a pyrrolobenzodiazepine (PBD) dimer via a maleimidocaproyl-valine-alanine linker. Serclutamab Talirine has the potential for use in advanced solid tumors associated with overexpression of the epidermal growth factor receptor (EGFR) or its ligands.