3-Chloro-L-tyrosine-13C6
Product Specifications
UNSPSC Description
3-Chloro-L-tyrosine-13C6 is the 13C labeled 3-Chloro-L-tyrosine[1]. 3-Chloro-L-tyrosine is a specific marker of myeloperoxidase-catalyzed oxidation, and is markedly elevated in low density lipoprotein isolated from human atherosclerotic intima[2].
Target Antigen
Endogenous Metabolite
Type
Isotope-Labeled Compounds
Related Pathways
Metabolic Enzyme/Protease
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/3-chloro-l-tyrosine-13c6.html
Purity
97.6
Solubility
10 mM in DMSO
Smiles
OC([C@H](C[13C]1=[13CH][13C](Cl)=[13C](O)[13CH]=[13CH]1)N)=O
Molecular Weight
221.59
References & Citations
[1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216.|[2]Hazen SL, et al. 3-Chlorotyrosine, a specific marker of myeloperoxidase-catalyzed oxidation, is markedly elevated in low density lipoprotein isolated from human atherosclerotic intima. J Clin Invest. 1997 May 1;99(9):2075-81.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-W041171S/3-Chloro-L-tyrosine-13C6-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-W041171S/3-Chloro-L-tyrosine-13C6-SDS-MedChemExpress.pdf
Clinical Information
No Development Reported
Curated Selection
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