(S, R, R) -VBY-825
(S, R, R) -VBY-825 is the isomer of VBY-825 , and can be used as an experimental control. VBY-825 is a novel reversible inhibitor of cathepsin with high inhibition of cathepsin B, L, S and V.
Product Specifications
UNSPSC
12352005
Target
Ser/Thr Protease
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/s-r-r-vby-825.html
Purity
98.01
Solubility
DMSO : 160 mg/mL (ultrasonic)
Smiles
CC[C@@H](C(C(NC1CC1)=O)=O)NC([C@H](CS(=O)(CC2CC2)=O)N[C@@H](C(F)(F)F)C3=CC=C(C=C3)F)=O
Molecular Formula
C23H29F4N3O5S
Molecular Weight
535.55
References & Citations
[1]Elie BT, et al. Identification and pre-clinical testing of a reversible cathepsin protease inhibitor reveals anti-tumor efficacy in a pancreatic cancer model. Biochimie. 2010 Nov;92 (11) :1618-24.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
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