Nitroflurbiprofen
Nitroflurbiprofen is a cyclooxygenase (COX) inhibitor with nitric oxide (NO) -donating properties, modulates the increased intrahepatic vascular tone in portal hypertensive cirrhotic rats.
Product Specifications
CAS Number
[158836-71-6]
Product Name Alternative
HCT 1206; NO-flurbiprofen; Nitroxybutyl flurbiprofen
UNSPSC
12352005
Target
COX
Type
Reference compound
Related Pathways
Immunology/Inflammation
Applications
COVID-19-immunoregulation
Field of Research
Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/Nitroflurbiprofen.html
Purity
99.64
Solubility
DMSO : 200 mg/mL (ultrasonic)
Smiles
O=C(OCCCCO[N+]([O-])=O)C(C)C1=CC=C(C2=CC=CC=C2)C(F)=C1
Molecular Formula
C19H20FNO5
Molecular Weight
361.36
References & Citations
[1]Laleman W, et al. Nitroflurbiprofen, a nitric oxide-releasing cyclooxygenase inhibitor, improves cirrhotic portalhypertension in rats. Gastroenterology. 2007 Feb;132 (2) :709-19.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
COX
Available Sizes
Curated Selection
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