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SMQ-03-20

SMQ-03-20 (compund 4g) is an orally bioavailable, brain-penetrant, selective and potent PDE11A4 inhibitor[1].

Product Specifications

UNSPSC

12352005

Target

Phosphodiesterase (PDE)

Type

Reference compound

Related Pathways

Metabolic Enzyme/Protease

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/pde11a4-in-2.html

Smiles

CN1N=CC=C1C2=CC(C3=NN=CS3)=C4C(N(N=C4C)C5=CC=C(C=C5)F)=N2

Molecular Formula

C19H14FN7S

Molecular Weight

391.42

References & Citations

[1]Mahmood SU, et al. First Demonstration of In Vivo PDE11A4 Target Engagement for Potential Treatment of Age-Related Memory Disorders. J Med Chem. 2024 Oct 10;67 (19) :17774-17784.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Frequently Asked Questions

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