Carbonic anhydrase inhibitor 28
Carbonic anhydrase inhibitor 28 (Compound 11) is a Pseudomonas aeruginosa carbonic anhydrase inhibitor. Carbonic anhydrase inhibitor 28 exhibits antimicrobial activity, with a MIC of 0.5 μg/mL and a MBC of 1 μg/mL against P. aeruginosa. Carbonic anhydrase inhibitor 28 can be used in anti-infection research[1].
Product Specifications
UNSPSC
12352005
Target
Antibiotic; Bacterial; Carbonic Anhydrase
Type
Reference compound
Related Pathways
Anti-infection; Metabolic Enzyme/Protease
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/carbonic-anhydrase-inhibitor-28.html
Smiles
OC1=CC=C(S(=O)(N)=O)C=C1NC(N2CCN(C3=C(F)C=C(C(C(C(O)=O)=CN4C5CC5)=O)C4=C3)CC2)=O
Molecular Formula
C24H24FN5O7S
Molecular Weight
545.54
References & Citations
[1]Marinacci B, et al. Inhibition of Pseudomonas aeruginosa Carbonic Anhydrases, Exploring Ciprofloxacin Functionalization Toward New Antibacterial Agents: An In-Depth Multidisciplinary Study. J Med Chem. 2024 Nov 14;67 (21) :19077-19102.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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