Carbonic anhydrase inhibitor 28

Carbonic anhydrase inhibitor 28 (Compound 11) is a Pseudomonas aeruginosa carbonic anhydrase inhibitor. Carbonic anhydrase inhibitor 28 exhibits antimicrobial activity, with a MIC of 0.5 μg/mL and a MBC of 1 μg/mL against P. aeruginosa. Carbonic anhydrase inhibitor 28 can be used in anti-infection research[1].

Product Specifications

UNSPSC

12352005

Target

Antibiotic; Bacterial; Carbonic Anhydrase

Type

Reference compound

Related Pathways

Anti-infection; Metabolic Enzyme/Protease

Field of Research

Infection

Assay Protocol

https://www.medchemexpress.com/carbonic-anhydrase-inhibitor-28.html

Smiles

OC1=CC=C(S(=O)(N)=O)C=C1NC(N2CCN(C3=C(F)C=C(C(C(C(O)=O)=CN4C5CC5)=O)C4=C3)CC2)=O

Molecular Formula

C24H24FN5O7S

Molecular Weight

545.54

References & Citations

[1]Marinacci B, et al. Inhibition of Pseudomonas aeruginosa Carbonic Anhydrases, Exploring Ciprofloxacin Functionalization Toward New Antibacterial Agents: An In-Depth Multidisciplinary Study. J Med Chem. 2024 Nov 14;67 (21) :19077-19102.