Lidoflazine
Lidoflazine is a high affinity blocker of the HERG (human ether-a-go-go-related gene) K+ channel. Lidoflazine is an antianginal calcium channel blocker that carries a significant risk of QT interval prolongation and ventricular arrhythmia[1].
Product Specifications
CAS Number
[3416-26-0]
UNSPSC
12352005
Target
Calcium Channel; Potassium Channel
Type
Reference compound
Related Pathways
Membrane Transporter/Ion Channel; Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/lidoflazine.html
Purity
98.10
Solubility
DMSO : 14 mg/mL (ultrasonic; warming)
Smiles
O=C(NC1=C(C)C=CC=C1C)CN2CCN(CCCC(C3=CC=C(F)C=C3)C4=CC=C(F)C=C4)CC2
Molecular Formula
C30H35F2N3O
Molecular Weight
491.62
References & Citations
[1]https://www.ncbi.nlm.nih.gov/pubmed/15135665
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
Launched
Isoform
Calcium Channel
Available Sizes
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