Anti-inflammatory agent 92

Anti-inflammatory agent 92 (compound LD4) is a porphyrin derivative. Anti-inflammatory agent 92 has anti-inflammatory properties. Anti-inflammatory agent 92 can alleviate ulcerative colitis by inhibiting the STAT3-EPHX2 axis[1].

Product Specifications

CAS Number

[1609387-77-0]

UNSPSC

12352005

Target

STAT

Type

Reference compound

Related Pathways

JAK/STAT Signaling; Stem Cell/Wnt

Field of Research

Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/anti-inflammatory-agent-92.html

Smiles

O=C([C@@H](N)CCCCN)NC(C=C1)=CC=C1/C(C(C=C/2)=NC2=C3\C4=CC=C(NC([C@@H](N)CCCCN)=O)C=C4)=C(N/5)\C=CC5=C(C6=CC=C(NC([C@@H](N)CCCCN)=O)C=C6)\C7=N/C(C=C7)=C(C8=CC=C(NC([C@@H](N)CCCCN)=O)C=C8)\C9=CC=C3N9

Molecular Formula

C68H82N16O4

Molecular Weight

1187.48

References & Citations

[1]Xu B, et al. Inhibition of the STAT3-EPHX2 axis promotes regression of ulcerative colitis by treatment with novel porphyrin derivative. Bioorg Chem. 2024 Sep;150:107579.