(R) -Olacaftor
(R) -Olacaftor ((R) -VX-440) is a Cystic fibrosis transmembrane conductance regulator (CFTR) modulator. (R) -Olacaftor has good potential for the study of cystic fibrosis (CF) [1].
Product Specifications
CAS Number
1899111-41-1
Product Name Alternative
(R) -VX-440
UNSPSC
12352005
Target
CFTR
Type
Reference compound
Related Pathways
Membrane Transporter/Ion Channel
Applications
Neuroscience-Neuromodulation
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/r-olacaftor.html
Purity
98.07
Solubility
DMSO : 250 mg/mL (ultrasonic)
Smiles
O=C(C1=CC=C(C2=CC(OCC(C)C)=CC(F)=C2)N=C1N3C(C)(C)C[C@@H](C)C3)NS(=O)(C4=CC=CC=C4)=O
Molecular Formula
C29H34FN3O4S
Molecular Weight
539.66
References & Citations
[1]Mark Thomas Miller, et al. Modulators of Cystic Fibrosis Transmembrane Conductance Regulator. Patent US20160095858A1.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C, 3 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
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