(R) -Olacaftor

(R) -Olacaftor ((R) -VX-440) is a Cystic fibrosis transmembrane conductance regulator (CFTR) modulator. (R) -Olacaftor has good potential for the study of cystic fibrosis (CF) [1].

Product Specifications

CAS Number

[1899111-41-1]

Product Name Alternative

(R) -VX-440

UNSPSC

12352005

Target

CFTR

Type

Reference compound

Related Pathways

Membrane Transporter/Ion Channel

Applications

Neuroscience-Neuromodulation

Field of Research

Others

Assay Protocol

https://www.medchemexpress.com/r-olacaftor.html

Purity

98.07

Solubility

DMSO : 250 mg/mL (ultrasonic)

Smiles

O=C(C1=CC=C(C2=CC(OCC(C)C)=CC(F)=C2)N=C1N3C(C)(C)C[C@@H](C)C3)NS(=O)(C4=CC=CC=C4)=O

Molecular Formula

C29H34FN3O4S

Molecular Weight

539.66

References & Citations

[1]Mark Thomas Miller, et al. Modulators of Cystic Fibrosis Transmembrane Conductance Regulator. Patent US20160095858A1.

Shipping Conditions

Blue Ice

Storage Conditions

-20°C, 3 years (Powder)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Available Sizes

Curated Selection

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