MD2-IN-1

MD2-IN-1 is an inhibitor of Myeloid differentiation protein 2 (MD2) with a KD of 189 μM for the recombinant human MD2 (rhMD2) .

Product Specifications

CAS Number

[111797-22-9]

UNSPSC

12352005

Hazard Statement

H302, H315, H319, H335

Target

Toll-like Receptor (TLR)

Type

Reference compound

Related Pathways

Immunology/Inflammation

Applications

COVID-19-immunoregulation

Field of Research

Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/MD2-IN-1.html

Purity

99.88

Solubility

DMSO : 50 mg/mL (ultrasonic)

Smiles

O=C(C1=CC=C(OC)C(OC)=C1)/C=C/C2=CC(OC)=C(OC)C(OC)=C2

Molecular Formula

C20H22O6

Molecular Weight

358.39

Precautions

H302, H315, H319, H335

References & Citations

[1]Zhang Y, et al. Discovery of new MD2 inhibitor from chalcone derivatives with anti-inflammatory effects in LPS-induced acute lung injury. Sci Rep. 2016 Apr 27;6:25130.

Shipping Conditions

Room Temperature

Storage Conditions

-20°C, 3 years; 4°C, 2 years (Powder)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Isoform

TLR4

Available Sizes

Curated Selection

Explore Other Products

Discover premium biology products from our extensive collection of 20M+ items

NBP3-09114JF646 0.1 mL

Rabbit Polyclonal Mycobacterium Tuberculosis ESAT6 Antibody [Janelia Fluor 646]

Ask

View Details

LS054433-20ug 20 µg

NOLA1 (GAR1) (NM_018983) Human Over-expression Lysate

Ask

View Details

SI204302B 1 Each

Rat Eif1ad Pre-designed siRNA Set B

Ask

View Details

ES17195-01 50 µL

CT173 rabbit pAb

Ask

View Details

ES17195-02 100 µL

CT173 rabbit pAb

Ask

View Details

A16449-100UG 100 µg

CCT8 Antibody

Ask

View Details