Clomiphene (citrate)
Product Specifications
UNSPSC Description
Clomiphene citrate (Clomifene citrate) is an orally active estrogen-receptor modulator. Clomiphene citrate has anti-cancer actixity, induces perturbations during meiotic maturation and cytogenetic abnormalities and ameliorates in managing psychiatric and cognitive impairment[1][2][3].
Target Antigen
Estrogen Receptor/ERR
Type
Reference compound
Related Pathways
Vitamin D Related/Nuclear Receptor
Field of Research
Cancer; Endocrinology; Neurological Disease
Assay Protocol
https://www.medchemexpress.com/clomiphene-citrate.html
Purity
99.69
Solubility
DMSO : ≥ 50 mg/mL|H2O : 1 mg/mL (ultrasonic)
Smiles
Cl/C(C1=CC=CC=C1)=C(C2=CC=CC=C2)/C3=CC=C(OCCN(CC)CC)C=C3.OC(CC(O)=O)(C(O)=O)CC(O)=O
Molecular Weight
598.08
References & Citations
[1]Jiann B P, et al. Effect of clomiphene on Ca2+ movement in human prostate cancer cells [J]. Life Sciences, 2002, 70(26): 3167-3178.|[2]London S N, et al. Clomiphene citrate-induced perturbations during meiotic maturation and cytogenetic abnormalities in mouse oocytes in vivo and in vitro [J]. Fertility and sterility, 2000, 73(3): 620-626.|[3]Akintoye O O, et al. Synergistic action of carvedilol and clomiphene in mitigating the behavioral phenotypes of letrozole-model of PCOS rats by modulating the NRF2/NFKB pathway [J]. Life Sciences, 2023, 324: 121737.Biochem Biophys Res Commun. 2020 Feb 19;522(4):862-868.|bioRxiv. 2020 May.|J Pharmaceut Biomed. 2020, 113870.|Patent. US11696914.|Viruses. 2021 Jun 28;13(7):1255.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, sealed storage, away from moisture)
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-B0463/Clomiphene-citrate-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-B0463/Clomiphene-citrate-SDS-MedChemExpress.pdf
Clinical Information
Launched
CAS Number
50-41-9
Available Sizes
Curated Selection
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