F-Amidine (TFA)
F-Amidine TFA is a Protein arginine deiminase 4 (PAD4) inhibitor. F-Amidine TFA can be used in the study of inflammatory and immune system diseases (such as rheumatoid arthritis) [1].
Product Specifications
CAS Number
877617-46-4
UNSPSC
12352005
Target
Protein Arginine Deiminase
Type
Reference compound
Related Pathways
Epigenetics
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/f-amidine-tfa.html
Solubility
10 mM in DMSO
Smiles
O=C(N[C@H](C(N)=O)CCCNC(CF)=N)C1=CC=CC=C1.O=C(O)C(F)(F)F
Molecular Formula
C16H20F4N4O4
Molecular Weight
408.35
References & Citations
[1]Li D, et al. Theoretical study of the mechanism of protein arginine deiminase 4 (PAD4) inhibition by F-amidine. J Mol Graph Model. 2015 Feb;55:25-32.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
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