CD73-IN-5
Product Specifications
UNSPSC Description
CD73-IN-5 is a potent and selective non-nucleotide small molecule inhibitor of CD73 (IC50 = 19 nM).
Target Antigen
CD73
Type
Reference compound
Related Pathways
Immunology/Inflammation
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/cd73-in-5.html
Solubility
DMSO : ≥ 50 mg/mL
Smiles
N#CC1=CC=C(CN2N=CC=C2C3=CC4=C(N=NN4C5=CC6=C(C=NN6)C=C5)C(F)=C3)C=C1
Molecular Weight
434.43
References & Citations
[1]Beatty JW, et al. Discovery of Potent and Selective Non-Nucleotide Small Molecule Inhibitors of CD73. J Med Chem. 2020 Apr 23;63(8):3935-3955.
Shipping Conditions
Room Temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-145334/CD73-IN-5-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-145334/CD73-IN-5-SDS-MedChemExpress.pdf
Clinical Information
No Development Reported
CAS Number
2412019-99-7
Available Sizes
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