CD73-IN-5
CD73-IN-5 is a potent and selective non-nucleotide small molecule inhibitor of CD73 (IC50 = 19 nM) .
Product Specifications
CAS Number
[2412019-99-7]
UNSPSC
12352005
Target
CD73
Type
Reference compound
Related Pathways
Immunology/Inflammation
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/cd73-in-5.html
Concentration
10mM
Purity
98.04
Solubility
DMSO : ≥ 50 mg/mL
Smiles
N#CC1=CC=C(CN2N=CC=C2C3=CC4=C(N=NN4C5=CC6=C(C=NN6)C=C5)C(F)=C3)C=C1
Molecular Formula
C24H15FN8
Molecular Weight
434.43
References & Citations
[1]Beatty JW, et al. Discovery of Potent and Selective Non-Nucleotide Small Molecule Inhibitors of CD73. J Med Chem. 2020 Apr 23;63 (8) :3935-3955.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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