Val-Cit-PAB-DEA-Duo-DM
Val-Cit-PAB-DEA-Duo-DM is a drug-linker conjugate, which consists of the linker Val-Cit-PAB, the spacer DEA and the ADC toxin Duocarmycin DM (Duo-DM). Val-Cit-PAB-DEA-Duo-DM can be used for the synthesis of ADC molecule[1].
Product Specifications
CAS Number
1698870-53-9
UNSPSC
12352203
Target
DNA Alkylator/Crosslinker; Drug-Linker Conjugates for ADC
Type
Reference compound
Related Pathways
Antibody-drug Conjugate/ADC Related; Cell Cycle/DNA Damage
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/val-cit-pab-dea-duo-dm.html
Smiles
ClC[C@H]1C2=C(C=C(C3=CC=CC=C32)OC(N(C)CCN(C)C(OCC4=CC=C(C=C4)NC([C@H](CCCNC(N)=O)NC([C@@H](N)C(C)C)=O)=O)=O)=O)N(C1)C(C5=CC6=CC(OCCN(C)C)=CC=C6N5)=O
Molecular Formula
C50H63ClN10O9
Molecular Weight
983.55
References & Citations
[1]Wu D, et al., Pegylated antibody hydroxyl-bearing drug conjugate. WO2023151679.
Shipping Conditions
Room temperature
Scientific Category
ADC Related
Clinical Information
No Development Reported
Frequently Asked Questions
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