3-Hydroxyacetophenone

3-Hydroxyacetophenone (m-Hydroxyacetophenone) is a hydroxy-substituted alkyl phenyl ketone and also a plant defensin in carnations. 3-Hydroxyacetophenone has antifusarium activity. In addition, 3-Hydroxyacetophenone can be used to synthesize Rivastigmine[2][3].

Product Specifications

CAS Number

121-71-1

Product Name Alternative

M-Hydroxyacetophenone

UNSPSC

12352005

Hazard Statement

H315, H319, H402

Target

Drug Intermediate; Fungal

Type

Natural Products

Related Pathways

Anti-infection; Others

Field of Research

Others

Assay Protocol

https://www.medchemexpress.com/3-hydroxyacetophenone.html

Concentration

10mM

Purity

99.99

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

CC(C1=CC=CC(O)=C1)=O

Molecular Formula

C8H8O2

Molecular Weight

136.15

Precautions

H315, H319, H402

References & Citations

[1]Katharine Moore Tibbetts, et al. Controlling dissociation of alkyl phenyl ketone radical cations in the strong-field regime through hydroxyl substitution position. J Phys Chem A. 2014 Sep 18;118 (37) :8170-6.|[2]Kiwon Han, et al. Chemoenzymatic synthesis of rivastigmine via dynamic kinetic resolution as a key step. J Org Chem. 2010 May 7;75 (9) :3105-8.|[3]Curir P, et al. 3-Hydroxyacetophenone in carnations is a phytoanticipin active against Fusarium oxysporum f. sp. dianthi. Phytochemistry, 1996, 41 (2) : 447-450.