Cytokeratin 20 Mouse mAb IHC Kit
Product Specifications
Background
CK20 is a cytokeratin with a molecular weight of 46 kDa, which is mainly expressed in gastrointestinal epithelium, urethral epithelium and Merkel cells. It is mainly used for the diagnosis of gastrointestinal adenocarcinoma, ovarian mucinous tumor, Merkel cell carcinoma and cholangiopancreatic adenocarcinoma. CK20 was negative in squamous cell carcinoma, lung adenocarcinoma, endometrial adenocarcinoma, breast cancer, small cell lung cancer and ovarian non mucinous tumor. It is often used in combination with CK7 and villin to judge the tissue source of adenocarcinoma.
Synonyms
CD20, CK 20, CK-20, CK20, CytokeRatin-20, CytokeRatin20, K1C20_HUMAN, K20, KA20, KeRatin 20, keRatin 20, type I, keRatin 21, Rat, homolog of, KeRatin, KeRatin type I cytoskeletal 20, KeRatin-20, KeRatin20, KRT 20, KRT 21, KRT20, KRT21, MGC35423, OTTHUMP00000164518, Protein IT, type I cytoskeletal 20
Gene Name
KRT20
Gene ID
54474
Swiss Prot
P35900
Reactivity
Human; Mouse; Rat
Immunogen
A synthetic peptide corresponding to the amino acid region 300 - 424 of the human Cytokeratin 20 protein.
Applications
Immunohistochemistry (IHC)
Dilution
It has been optimized for direct use, requiring no further dilution.
Specificity
The antibody can specifically recognize human CK20 protein, and shows no cross reaction with CK1, 5, 6, 7, 8, 13, 14, 15, 17, 18.
Formulation
The ready - to - use antibody is provided in liquid form in phosphate buffer saline containing stabilizing protein and 0. 05% Proclin 300.
Subcellular Location
Cytoplasmic, Membranous
Protein Name
Cytokeratin 20
Available Sizes
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