CD61 Mouse mAb IHC Kit
Product Specifications
Background
CD61 is also known as integrin β 3, a 105kDa membrane glycoprotein, is an integrin cell surface protein related to cell adhesion and cell surface mediated signal transduction. It is expressed on platelets, megakaryocytes, osteoclasts and vascular endothelial cells. CD61 and CD41 form platelet glycoprotein IIb / IIIB complex and participate in coagulation and thrombosis. It is mainly used to detect small megakaryocytes in platelet and bone marrow biopsy, and can also be used in the diagnosis of megakaryocytic leukemia.
Synonyms
BDPLT16, BDPLT2, CD 61, CD61, CD61 antigen, GP3A, GPIIIa, GT, HPA 1, HPA 4, Integrin beta 3 (platelet glycoprotein IIIa antigen CD61), Integrin beta chain beta 3, Integrin beta-3, ITB3_HUMAN, ITG B3, ITGB 3, ITGB3, NAIT, platelet fibrinogen receptor, Platelet fibrinogen receptor beta subunit, Platelet fibrinogen receptor, beta subunit, Platelet glycoprotein IIIa, Platelet glycoprotein IIIa precursor, Platelet membrane glycoprotein IIIa, PTP
Gene Name
ITGB3 GP3A
Gene ID
3690
Swiss Prot
P05106
Reactivity
Human
Immunogen
A synthetic peptide corresponding to the amino acid region 1 - 100 of the human CD61 protein.
Applications
Immunohistochemistry (IHC)
Dilution
It has been optimized for direct use, requiring no further dilution.
Specificity
The antibody can specifically recognize human CD61 protein.
Formulation
The ready - to - use antibody is provided in liquid form in phosphate buffer saline containing stabilizing protein and 0. 05% Proclin 300.
Subcellular Location
Membranous, Cytoplasmic
Protein Name
CD61
Available Sizes
Curated Selection
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