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Topoisomerase IIα Rabbit mAb IHC Kit

Product Specifications

Background

Topoisomerase IIα (Topo IIα) is a nuclear protein with a molecular weight of 170 kDa. It belongs to the topoisomerase family and is expressed in proliferating cells. The main function is to maintain the spatial conformation of DNA and ensure its function. It is mainly used for the study of drug resistance.

Synonyms

Alpha isozyme; ATP hydrolyzing DNA topoisomerase II alfa; DNA gyrase; DNA topoisomerase (ATP hydrolyzing) ; DNA topoisomerase 2 alpha; DNA topoisomerase 2-alpha; DNA topoisomerase II 170 kD; DNA topoisomerase II alpha isozyme; DNA topoisomerase II; DNA Topoisomerase2; TOP 2A; TOP2; TOP2A; TOP2A_HUMAN; Topoisomerase DNA II alpha 170 kDa; TP2A

Gene Name

TOP2A

Gene ID

7153

Swiss Prot

P11388

Reactivity

Human; Mouse; (predicted: Rat)

Immunogen

A synthetic peptide corresponding to the amino acid region 1400 - 1531 of the human Topoisomerase IIα protein.

Applications

Immunohistochemistry (IHC)

Dilution

It has been optimized for direct use, requiring no further dilution.

Specificity

The antibody can specifically recognize human Topoisomerase IIα protein.

Formulation

The ready - to - use antibody is provided in liquid form in phosphate buffer saline containing stabilizing protein and 0. 05% Proclin 300.

Subcellular Location

Nuclear

Protein Name

Topoisomerase IIα

Available Sizes

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