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Thyroid transcription factor-1 (TTF1) Rabbit mAb IHC Kit

Product Specifications

Background

Thyroid transcription factor 1 (TTF-1) is a nuclear protein with a molecular weight of 38-40 kDa. It is the basic material for thyroid differentiation and the regulation of thyroglobulin secretion. It can promote the transport of thyroid peroxidase and iodine / sodium. TTF-1 is mainly distributed in type II alveolar epithelium, respiratory epithelium and Clara cells of thyroid and lung in adult tissues, but it is not expressed in type I alveolar epithelium. It is mainly used for the diagnosis of small cell lung cancer, the differential diagnosis of primary lung adenocarcinoma from metastatic adenocarcinoma, and the differential diagnosis of lung cancer from malignant mesothelioma and paraganglioma of pleura.

Synonyms

AV026640; BCH; Benign chorea; BHC; Homeobox protein NK 2 homolog A; Homeobox protein NK-2 homolog A; Homeobox protein Nkx 2. 1; Homeobox protein Nkx-2. 1; Homeobox protein Nkx2. 1; NK 2; NK 2 homolog A; NK2; NK2 homeobox 1; NK2, drosophila, homolog of, A; NK2. 1, Mouse, homolog of; Nkx 2 1; NKX 2. 1; NKX 2A; NKX2 1; Nkx2-1; NKX2. 1; NKX21_HUMAN; NKX2A; T EBP; T/EBP; TEBP; Thyroid nuclear factor 1; Thyroid nuclear factor; Thyroid specific enhancer binding protein; Thyroid transcription factor 1; Tin man; Tinman; TITF 1; TITF1; TTF 1; TTF-1; TTF1

Gene Name

NKX2-1

Gene ID

7080

Swiss Prot

P43699

Reactivity

Human; Mouse; (predicted: Rat)

Immunogen

A synthetic peptide corresponding to the amino acid region 50 - 150 of the human Thyroid transcription factor - 1 protein.

Applications

Immunohistochemistry (IHC)

Dilution

It has been optimized for direct use, requiring no further dilution.

Specificity

The antibody can specifically recognize human TTF1 protein.

Formulation

The ready - to - use antibody is provided in liquid form in phosphate buffer saline containing stabilizing protein and 0. 05% Proclin 300.

Subcellular Location

Nuclear

Protein Name

Thyroid transcription factor-1

Available Sizes

Frequently Asked Questions

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