Progesterone Receptor (PR) Rabbit mAb IHC Kit
Product Specifications
Background
There are two isoforms of progesterone receptor, PRA (94kDa) PRB (114kDa), which exist in normal endometrium and breast epithelial cells. Their function is to regulate the expression of genes as transcription factors and affect cytotoxic proliferation and differentiation. A large number of studies show that breast cancer patients with positive ER and PR have good endocrine therapy effect, high remission rate, low recurrence rate and good prognosis. Therefore, PR has been used as a routine examination item for breast cancer patients.
Synonyms
Progesterone receptor; PR; Nuclear receptor subfamily 3 group C member 3
Gene Name
PGR NR3C3
Gene ID
5241
Swiss Prot
P06401
Reactivity
Human; (predicted: Mouse; Rat; Rabbit)
Immunogen
A synthetic peptide corresponding to the amino acid region 200 - 300 of the human Progesterone Receptor protein.
Applications
Immunohistochemistry (IHC)
Dilution
It has been optimized for direct use, requiring no further dilution.
Specificity
The antibody can specifically recognize human Progesterone Receptor protein.
Formulation
The ready - to - use antibody is provided in liquid form in phosphate buffer saline containing stabilizing protein and 0. 05% Proclin 300.
Subcellular Location
Nuclear
Protein Name
Progesterone Receptor
Available Sizes
Curated Selection
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