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Perforin Rabbit mAb IHC Kit

Product Specifications

Background

Perforin is a specific marker of activated cytotoxic T cells and natural killer cells. It can destroy the corresponding target cell membrane and induce apoptosis. It is mainly expressed in CD3 negative and CD56 positive NK cells, CD3 positive large granular lymphocytes and γδ Type T cells. It is mainly used for the auxiliary diagnosis of NK cell lymphoma and NK cell like T-cell lymphoma.

Synonyms

Cytolysin; FLH2; HPLH2; Lymphocyte pore-forming protein; P1; PERF_HUMAN; perforin 1 (pore forming protein) ; Perforin 1; Perforin-1; PFP; PGFL; PIGF; PIGF-2; PLGF; Pore forming protein; prf1; SHGC-10760

Gene Name

PRF1

Gene ID

5551

Swiss Prot

P14222

Reactivity

Human

Immunogen

A synthetic peptide corresponding to the amino acid region 1 - 100 of the human Perforin protein.

Applications

Immunohistochemistry (IHC)

Dilution

It has been optimized for direct use, requiring no further dilution.

Specificity

The antibody can specifically recognize human Perforin protein.

Formulation

The ready - to - use antibody is provided in liquid form in phosphate buffer saline containing stabilizing protein and 0. 05% Proclin 300.

Subcellular Location

Cytoplasmic

Protein Name

Perforin

Available Sizes

Frequently Asked Questions

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