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IRF-4/MUM1 Rabbit mAb IHC Kit

Product Specifications

Background

MUM1, also known as interferon regulatory factor 4, with a molecular weight of 50 kDa, is a nuclear transcription factor necessary for the development and activation of B lymphocytes. It can regulate the proliferation and differentiation of B cells and activate T lymphocytes. It is mainly used for the study of B-cell lymphoma. It is expressed in multiple myeloma, lymphoplasmacytic lymphoma and diffuse large B-cell lymphoma. It can be used as a tissue derived immunophenotypic marker of B-cell lymphoma. At the same time, it is also expressed in RS cells in anaplastic large cell lymphoma, peripheral T-cell lymphoma and classical Hodgkin's lymphoma. It is an immunophenotypic marker of malignant lymphoma, only limited to lymphocytes and melanocytes.

Synonyms

Interferon regulatory factor 4; IRF 4; IRF-4; Irf4; IRF4_HUMAN; LSIRF; Lymphocyte specific interferon regulatory factor; Lymphocyte specific IRF; Lymphocyte-specific interferon regulatory factor; Multiple myeloma oncogene 1; MUM 1; MUM1; NF EM5; NF-EM5; NFEM5; PU. 1 interaction partner; Sfpi1/PU. 1 interaction partner; Transcriptional activator PIP

Gene Name

IRF4

Gene ID

3662

Swiss Prot

Q15306

Reactivity

Human

Immunogen

A synthetic peptide corresponding to the amino acid region 350 - 451 of the human IRF - 4/MUM1 protein.

Applications

Immunohistochemistry (IHC)

Dilution

It has been optimized for direct use, requiring no further dilution.

Specificity

The antibody can specifically recognize human MUM1 protein.

Formulation

The ready - to - use antibody is provided in liquid form in phosphate buffer saline containing stabilizing protein and 0. 05% Proclin 300.

Subcellular Location

Nuclear

Protein Name

MUM1

Available Sizes

Frequently Asked Questions

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