IGF-2 Rabbit mAb IHC Kit
Product Specifications
Background
Insulin-like growth factor II (IGF-2) is the protein hormones which belongs to the family of insulin-like growth factors that share structural similarity to insulin. It is secreted by the liver and circulates in the blood. In fetal, IGF-2 is a major growth factor that regulating fetoplacental development influenced by placental lactogen. It is also involed in tissue differentiation. In adults, IGF-2 is involved in glucose metabolism in liver, adipose tissue and skeletal muscle. It is an imprinted gene, expressed only from the paternal allele. Loss of imprinting is associated with Beckwith-Wiedemann syndrome.
Synonyms
C11orf43; IGF 2; IGF II; IGF-II; IGF2; IGF2_HUMAN; IGFII; INSIGF; insulin like growth factor 2 (somatomedin A) ; Insulin like Growth Factor 2; Insulin like growth factor II; Insulin like growth factor II precursor; Insulin like growth factor type 2; pp9974; Preptin; putative insulin like growth factor II associated protein; Somatomedin A; Somatomedin-A
Gene Name
IGF2
Gene ID
3481
Swiss Prot
P01344
Reactivity
Human
Immunogen
A synthetic peptide corresponding to the amino acid region 1 - 100 of the human IGF - 2 protein.
Applications
Immunohistochemistry (IHC)
Dilution
It has been optimized for direct use, requiring no further dilution.
Specificity
The antibody can specifically recognize human IGF-2 protein.
Formulation
The ready - to - use antibody is provided in liquid form in phosphate buffer saline containing stabilizing protein and 0. 05% Proclin 300.
Subcellular Location
Cytoplasmic
Protein Name
IGF-2
Available Sizes
Frequently Asked Questions
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