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IGF-2 Rabbit mAb IHC Kit

Product Specifications

Background

Insulin-like growth factor II (IGF-2) is the protein hormones which belongs to the family of insulin-like growth factors that share structural similarity to insulin. It is secreted by the liver and circulates in the blood. In fetal, IGF-2 is a major growth factor that regulating fetoplacental development influenced by placental lactogen. It is also involed in tissue differentiation. In adults, IGF-2 is involved in glucose metabolism in liver, adipose tissue and skeletal muscle. It is an imprinted gene, expressed only from the paternal allele. Loss of imprinting is associated with Beckwith-Wiedemann syndrome.

Synonyms

C11orf43; IGF 2; IGF II; IGF-II; IGF2; IGF2_HUMAN; IGFII; INSIGF; insulin like growth factor 2 (somatomedin A) ; Insulin like Growth Factor 2; Insulin like growth factor II; Insulin like growth factor II precursor; Insulin like growth factor type 2; pp9974; Preptin; putative insulin like growth factor II associated protein; Somatomedin A; Somatomedin-A

Gene Name

IGF2

Gene ID

3481

Swiss Prot

P01344

Reactivity

Human

Immunogen

A synthetic peptide corresponding to the amino acid region 1 - 100 of the human IGF - 2 protein.

Applications

Immunohistochemistry (IHC)

Dilution

It has been optimized for direct use, requiring no further dilution.

Specificity

The antibody can specifically recognize human IGF-2 protein.

Formulation

The ready - to - use antibody is provided in liquid form in phosphate buffer saline containing stabilizing protein and 0. 05% Proclin 300.

Subcellular Location

Cytoplasmic

Protein Name

IGF-2

Available Sizes

Frequently Asked Questions

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