Glypican-3 (GPC3) Rabbit mAb IHC Kit
Product Specifications
Background
Glypican 3 is a carcinoembryonic protein and belongs to the heparan sulfate polysaccharide family. It is mainly expressed in fetal liver, kidney and trophoblast, but not in other normal tissues. Glypican 3 is a sensitive and specific marker of hepatocellular carcinoma. Its expression is related to differentiation. The lower the degree of differentiation, the higher the expression. It is highly expressed in ovarian yolk sac tumor, choriocarcinoma and melanoma.
Synonyms
DGSX; Glypican proteoglycan 3; Glypican-3 [Precursor]; Gpc3; GPC3_HUMAN; GTR2 2; GTR2-2; Heparan sulphate proteoglycan; Intestinal protein OCI 5; Intestinal protein OCI-5; MXR7; OCI 5; OCI-5; OCI5; SDYS; Secreted glypican-3; SGB; SGBS; SGBS1
Gene Name
GPC3
Gene ID
2719
Swiss Prot
P51654
Reactivity
Human
Immunogen
A synthetic peptide corresponding to the amino acid region 400 - 500 of the human Glypican - 3 protein.
Applications
Immunohistochemistry (IHC)
Dilution
It has been optimized for direct use, requiring no further dilution.
Specificity
The antibody can specifically recognize human Glypican-3 protein.
Formulation
The ready - to - use antibody is provided in liquid form in phosphate buffer saline containing stabilizing protein and 0. 05% Proclin 300.
Subcellular Location
Cytoplasmic
Protein Name
Glypican-3
Available Sizes
Curated Selection
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