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Glypican-3 (GPC3) Rabbit mAb IHC Kit

Product Specifications

Background

Glypican 3 is a carcinoembryonic protein and belongs to the heparan sulfate polysaccharide family. It is mainly expressed in fetal liver, kidney and trophoblast, but not in other normal tissues. Glypican 3 is a sensitive and specific marker of hepatocellular carcinoma. Its expression is related to differentiation. The lower the degree of differentiation, the higher the expression. It is highly expressed in ovarian yolk sac tumor, choriocarcinoma and melanoma.

Synonyms

DGSX; Glypican proteoglycan 3; Glypican-3 [Precursor]; Gpc3; GPC3_HUMAN; GTR2 2; GTR2-2; Heparan sulphate proteoglycan; Intestinal protein OCI 5; Intestinal protein OCI-5; MXR7; OCI 5; OCI-5; OCI5; SDYS; Secreted glypican-3; SGB; SGBS; SGBS1

Gene Name

GPC3

Gene ID

2719

Swiss Prot

P51654

Reactivity

Human

Immunogen

A synthetic peptide corresponding to the amino acid region 400 - 500 of the human Glypican - 3 protein.

Applications

Immunohistochemistry (IHC)

Dilution

It has been optimized for direct use, requiring no further dilution.

Specificity

The antibody can specifically recognize human Glypican-3 protein.

Formulation

The ready - to - use antibody is provided in liquid form in phosphate buffer saline containing stabilizing protein and 0. 05% Proclin 300.

Subcellular Location

Cytoplasmic

Protein Name

Glypican-3

Available Sizes

Curated Selection

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