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Epithelial Membrane Antigen (MUC1) Rabbit mAb IHC Kit

Product Specifications

Background

MUC1 is a type I transmembrane protein with a molecular weight of 450 kDa. One of the characteristics of glandular epithelial tissue is the synthesis and secretion of MUC1. It plays an important role in epithelial renewal and differentiation, maintaining epithelial integrity and carcinogenesis and metastasis. Under normal conditions, it is mainly expressed in a variety of tissues and organs, epithelial cells near the lumen or glandular cavity, showing apical expression and polar distribution. It is also expressed in T cells, B cells and dendritic cells of hematopoietic system. It is mainly used to identify tumors of epithelial origin.

Synonyms

ADMCKD; ADMCKD1; Breast carcinoma associated antigen DF3; Breast carcinoma-associated antigen DF3; CA 15-3; CA15 3; CA15 3 antigen; CA15-3; CA15. 3; Cancer antigen 15-3; Carcinoma associated mucin; Carcinoma-associated mucin; CD 227; CD227; DF3 antigen; EMA; Episialin; Epithelial Membrane Antigen; H23 antigen; H23AG; KL 6; KL-6; KL6; Krebs von den Lungen-6; MAM 6; MAM6; MCD; MCKD; MCKD1; Medullary cystic kidney disease 1 (autosomal dominant) ; Medullary cystic kidney disease, autosomal dominant; MUC 1; MUC-1; MUC-1/SEC; MUC-1/X; MUC1; MUC1-alpha; MUC1-beta; MUC1-CT; MUC1-NT; MUC1/ZD; MUC1_HUMAN; Mucin 1; Mucin 1 cell surface associated; Mucin 1 transmembrane; Mucin 1, cell surface associated; Mucin-1 subunit beta; Peanut reactive urinary mucin; Peanut-reactive urinary mucin; PEM; PEMT; Polymorphic epithelial mucin; PUM; Tumor associated epithelial membrane antigen; Tumor associated epithelial mucin; Tumor associated mucin; Tumor-associated epithelial membrane antigen; Tumor-associated mucin

Gene Name

MUC1

Gene ID

4582

Swiss Prot

P15941

Reactivity

Human

Immunogen

A synthetic peptide corresponding to the amino acid region 100 - 200 of the human MUC1 protein.

Applications

Immunohistochemistry (IHC)

Dilution

It has been optimized for direct use, requiring no further dilution.

Specificity

The antibody can specifically recognize human MUC1 protein.

Formulation

The ready - to - use antibody is provided in liquid form in phosphate buffer saline containing stabilizing protein and 0. 05% Proclin 300.

Subcellular Location

Cytoplasmic, Membranous

Protein Name

Epithelial Membrane Antigen

Available Sizes

Frequently Asked Questions

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