Ep-CAM Rabbit mAb IHC Kit
Product Specifications
Background
Ep-CAM consists of two glycoproteins, 34 and 39 kDa, sometimes designated epithelial antigen, epithelial specific antigen, and epithelial glycoprotein. The glycoproteins are located on the cell membrane surface and in the cytoplasm of virtually all epithelial cells with the exception of most squamous epithelia, hepatocytes, renal proximal tubular cells, gastric parietal cells and myoepithelial cells. Ep-CAM is found in the majority of adenocarcinomas. The antibody is used for differential diagnosis of adenocarcinoma from malignant mesothelioma.
Synonyms
Epithelial cell adhesion molecule; Ep-CAM; Adenocarcinoma-associated antigen; Cell surface glycoprotein Trop-1; Epithelial cell surface antigen; Epithelial glycoprotein (EGP) ; Epithelial glycoprotein 314 (EGP314; hEGP314) ; CD326
Gene Name
EPCAM GA733-2 M1S2 M4S1 MIC18 TACSTD1 TROP1
Gene ID
4072
Swiss Prot
P16422
Reactivity
Human
Immunogen
A synthetic peptide corresponding to the amino acid region 100 - 200 of the human Ep - CAM protein.
Applications
Immunohistochemistry (IHC)
Dilution
It has been optimized for direct use, requiring no further dilution.
Specificity
The antibody can recognize human Ep-CAM protein.
Formulation
The ready - to - use antibody is provided in liquid form in phosphate buffer saline containing stabilizing protein and 0. 05% Proclin 300.
Subcellular Location
Membranous
Protein Name
Ep-CAM
Available Sizes
Curated Selection
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