Cytokeratin 14 (CK14) Rabbit mAb IHC Kit

Product Specifications

Background

CK14 is a member of the Type I family of cytokeratins with a molecular weight of 50kDa, which is expressed in the basal cells of myoepithelium and keratinized squamous epithelium. It is mainly used for the difference between stratified squamous epithelium and monolayer epithelium and the diagnosis of squamous cell carcinoma. Eosinophilic tumors at multiple anatomical sites express CK14, which can be used to distinguish from adenocarcinoma, invasive ductal carcinoma of salivary gland and intraductal carcinoma.

Synonyms

CK 14; CK-14; ck14; Cytokeratin 14; CytokeRatin-14; CytokeRatin14; Dowling Meara; EBS3; EBS4; Epidermolysis bullosa simplex; K14; K1C14_HUMAN; KeRatin 14 (epidermolysis bullosa simplex, Dowling-Meara, Koebner) ; KeRatin 14; KeRatin; KeRatin type I cytoskeletal 14; KeRatin, type I cytoskeletal 14; KeRatin-14; KeRatin14; Koebner; Krt 14; Krt14; NFJ; OTTHUMP00000164624; type I cytoskeletal 14

Gene Name

KRT14

Gene ID

3861

Swiss Prot

P02533

Reactivity

Human; (predicted: Mouse; Rat)

Immunogen

A synthetic peptide corresponding to the amino acid region 400 - 472 of the human Cytokeratin 14 protein.

Applications

Immunohistochemistry (IHC)

Dilution

It has been optimized for direct use, requiring no further dilution.

Specificity

The antibody can specifically recognize human CK14 protein. In immunohistochemistry on formalin-fixed, paraffin-embedded tissue sections, the antibody specifically labels the basal cell of squamous epithelial cells and glandular epithelia, myoepithelium and mesothelial cells.