Claudin 7 Rabbit mAb IHC Kit
Product Specifications
Background
Claudin 7 is a 22 kDa membrane protein, belonging to the tight junction protein family. Claudin family proteins play an important role in cell polarity, signal transduction and the pathogenesis of a variety of malignant tumors. It has been reported that compared with non neoplastic mucosal tissues, the expression of claudin 7 in laryngeal squamous cell carcinoma is down-regulated, and the expression level is related to distant metastasis, which can be used as a potential predictor of poor prognosis. Therefore, claudin 7 may be a useful immunohistochemical marker for the diagnosis, metastasis and prognosis of laryngeal cancer.
Synonyms
CEPTR L2; CEPTRL 2; CEPTRL2; Claudin 1; Claudin 7; Claudin 9; Claudin-7; Claudin1; Claudin7; Claudin9; CLD7_HUMAN; CLDN 7; CLDN-7; CLDN7; Clostridium perfringens enterotoxin receptor like 2; CPETR L2; CPETRL 2; CPETRL2; Hs. 84359
Gene Name
CLDN7 CEPTRL2 CPETRL2
Gene ID
1366
Swiss Prot
O95471
Reactivity
Human; Mouse (predicted: Rat)
Immunogen
A synthetic peptide corresponding to the amino acid region 100 - 211 of the human Claudin 7 protein.
Applications
Immunohistochemistry (IHC)
Dilution
It has been optimized for direct use, requiring no further dilution.
Specificity
The antibody can specifically recognize human Claudin 7 protein.
Formulation
The ready - to - use antibody is provided in liquid form in phosphate buffer saline containing stabilizing protein and 0. 05% Proclin 300.
Subcellular Location
Membranous
Protein Name
Claudin 7
Available Sizes
Curated Selection
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