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CD61 Rabbit mAb IHC Kit

Product Specifications

Background

CD61 is also known as integrin β 3, a 105kDa membrane glycoprotein, is an integrin cell surface protein related to cell adhesion and cell surface mediated signal transduction. It is expressed on platelets, megakaryocytes, osteoclasts and vascular endothelial cells. CD61 and CD41 form platelet glycoprotein IIb / IIIB complex and participate in coagulation and thrombosis. It is mainly used to detect small megakaryocytes in platelet and bone marrow biopsy, and can also be used in the diagnosis of megakaryocytic leukemia.

Synonyms

BDPLT16; BDPLT2; CD 61; CD61; CD61 antigen; GP3A; GPIIIa; GT; HPA 1; HPA 4; Integrin beta 3 (platelet glycoprotein IIIa antigen CD61) ; Integrin beta chain beta 3; Integrin beta-3; ITB3_HUMAN; ITG B3; ITGB 3; ITGB3; NAIT; platelet fibrinogen receptor; Platelet fibrinogen receptor beta subunit; Platelet fibrinogen receptor, beta subunit; Platelet glycoprotein IIIa; Platelet glycoprotein IIIa precursor; Platelet membrane glycoprotein IIIa; PTP

Gene Name

ITGB3

Gene ID

3690

Swiss Prot

P05106

Reactivity

Human

Immunogen

A synthetic peptide corresponding to the amino acid region 1 - 100 of the human CD61 protein.

Applications

Immunohistochemistry (IHC)

Dilution

It has been optimized for direct use, requiring no further dilution.

Specificity

The antibody can specifically recognize human CD61 protein.

Formulation

The ready - to - use antibody is provided in liquid form in phosphate buffer saline containing stabilizing protein and 0. 05% Proclin 300.

Subcellular Location

Cytoplasmic

Protein Name

CD61

Available Sizes

Curated Selection

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