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CD45 (LCA) Rabbit mAb IHC Kit

Product Specifications

Background

CD45, also known as leukocyte common antigen, is a specific marker of hematopoietic cells. CD45 consists of at least four isoforms produced by alternative messenger RNA splicing. The isoforms share a common large intracellular domain and the extracellular domains are rod shaped, heavily glycosylated. It is expressed in all T cells, B cells and NK cells except plasma cells, monocytes, granulocytes and macrophages, but not in erythrocytes, platelets and non hematopoietic systems, Therefore, it can be used as a good marker to distinguish lymphoma or leukemia from non hematopoietic tumors.

Synonyms

B220; CD 45; CD45; CD45 antigen; CD45R; GP180; L-CA; LCA; Leukocyte common antigen; loc; Ly-5; LY5; Ly5, homolog of; Lyt-4; OTTHUMP00000033813; OTTHUMP00000033816; OTTHUMP00000033817; OTTHUMP00000038574; Protein tyrosine phosphatase receptor type c polypeptide; Protein tyrosine phosphatase, receptor type C; protein tyrosine phosphatase, receptor type, C; Protein tyrosine phosphatase, receptor type, c polypeptide; Ptprc; PTPRC_HUMAN; Receptor-type tyrosine-protein phosphatase C; T200; T200 glycoprotein; T200 leukocyte common antigen

Gene Name

PTPRC

Gene ID

5788

Swiss Prot

P08575-3

Reactivity

Human

Immunogen

A synthetic peptide corresponding to the amino acid region 500 - 600 of the human CD45 protein.

Applications

Immunohistochemistry (IHC)

Dilution

It has been optimized for direct use, requiring no further dilution.

Specificity

The antibody can specifically recognize human CD45 protein, including CD45RA, CD45RB and CD45RO.

Formulation

The ready - to - use antibody is provided in liquid form in phosphate buffer saline containing stabilizing protein and 0. 05% Proclin 300.

Subcellular Location

Membranous

Protein Name

CD45

Available Sizes

Curated Selection

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