CD45 (LCA) Rabbit mAb IHC Kit
Product Specifications
Background
CD45, also known as leukocyte common antigen, is a specific marker of hematopoietic cells. CD45 consists of at least four isoforms produced by alternative messenger RNA splicing. The isoforms share a common large intracellular domain and the extracellular domains are rod shaped, heavily glycosylated. It is expressed in all T cells, B cells and NK cells except plasma cells, monocytes, granulocytes and macrophages, but not in erythrocytes, platelets and non hematopoietic systems, Therefore, it can be used as a good marker to distinguish lymphoma or leukemia from non hematopoietic tumors.
Synonyms
B220; CD 45; CD45; CD45 antigen; CD45R; GP180; L-CA; LCA; Leukocyte common antigen; loc; Ly-5; LY5; Ly5, homolog of; Lyt-4; OTTHUMP00000033813; OTTHUMP00000033816; OTTHUMP00000033817; OTTHUMP00000038574; Protein tyrosine phosphatase receptor type c polypeptide; Protein tyrosine phosphatase, receptor type C; protein tyrosine phosphatase, receptor type, C; Protein tyrosine phosphatase, receptor type, c polypeptide; Ptprc; PTPRC_HUMAN; Receptor-type tyrosine-protein phosphatase C; T200; T200 glycoprotein; T200 leukocyte common antigen
Gene Name
PTPRC
Gene ID
5788
Swiss Prot
P08575-3
Reactivity
Human
Immunogen
A synthetic peptide corresponding to the amino acid region 500 - 600 of the human CD45 protein.
Applications
Immunohistochemistry (IHC)
Dilution
It has been optimized for direct use, requiring no further dilution.
Specificity
The antibody can specifically recognize human CD45 protein, including CD45RA, CD45RB and CD45RO.
Formulation
The ready - to - use antibody is provided in liquid form in phosphate buffer saline containing stabilizing protein and 0. 05% Proclin 300.
Subcellular Location
Membranous
Protein Name
CD45
Available Sizes
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
