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CD23 Rabbit mAb IHC Kit

Product Specifications

Background

CD23 is a low affinity IgE receptor with a molecular weight of 45-60kDa. It is a B cell specific antigen. Its main function is to regulate IgE production and B cell differentiation. CD23 is mainly expressed in B cells activated in the germinal center of lymphoid follicles, mature IgD positive B lymphocytes and follicular dendritic cells (bright area) . It is also used for labeling monocytes. For the study of lymphohematopoietic diseases, it is positive in small B-lymphocyte lymphoma / chronic lymphocytic leukemia and mediastinal large B-cell lymphoma, occasionally positive in some Hodgkin's lymphoma and negative in mantle cell lymphoma.

Synonyms

Blast 2; BLAST-2; Blast2; C type lectin domain family 4 member J; C-type lectin domain family 4; C-type lectin domain family 4 member J; C-type lectin domain family 4, member J; CD 23; CD 23A; CD23; CD23 antigen; CD23A; CLEC 4J; CLEC4J; Fc epsilon receptor II; Fc epsilon RII; Fc fragment of IgE; Fc fragment of IgE low affinity II receptor for; Fc fragment of IgE receptor II; Fc fragment of IgE, low affinity II, receptor for (CD23) ; Fc of IgE; Fc of IgE, low affinity II, receptor for (CD23) ; Fc receptor IgE low affinity II alpha polypeptide; Fc receptor, IgE, low affinity II, alpha polypeptide, isoform CRA_a; Fc-epsilon-RII; FCE 2; FCE2; FCER 2; Fcer2; FCER2_HUMAN; FCER2A; FceRII; IgE binding factor; IgE receptor lymphocyte; IgE-binding factor; IGEBF; Immunoglobulin E binding factor; Immunoglobulin E receptor; Immunoglobulin E receptor, low affinity II; Immunoglobulin E-binding factor; Immunoglobulin epsilon chain; LEUKOCYTE ANTIGEN CD23; Low Affinity IgE Receptor; Low affinity immunoglobulin epsilon Fc receptor; Low affinity immunoglobulin epsilon Fc receptor membrane bound form; Low affinity immunoglobulin epsilon Fc receptor soluble form; Ly-42; Ly42; Lymphocyte antigen CD23; Lymphocyte IgE receptor; MGC93219

Gene Name

FCER2

Gene ID

2208

Swiss Prot

P06734

Reactivity

Human

Immunogen

A synthetic peptide corresponding to the amino acid region 200 - 321 of the human CD23 protein.

Applications

Immunohistochemistry (IHC)

Dilution

It has been optimized for direct use, requiring no further dilution.

Specificity

The antibody can specifically recognize human CD23 protein.

Formulation

The ready - to - use antibody is provided in liquid form in phosphate buffer saline containing stabilizing protein and 0. 05% Proclin 300.

Subcellular Location

Membranous

Protein Name

CD23

Available Sizes

Curated Selection

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