CD105 (Endoglin) Rabbit mAb IHC Kit
Product Specifications
Background
CD105 is a homodimeric cell membrane glycoprotein linked by disulfide bonds. It is a new class of cell adhesion molecules and plays an important role in regulating angiogenesis. As a receptor of TGF-beta, CD105 is highly expressed in vascular endothelial cells of tumor related neovascular endothelium. Therefore, the evaluation of tumor microvessel density by immunohistochemical staining is significantly correlated with tumor invasion and prognosis.
Synonyms
AI528660; AI662476; CD 105; CD105; CD105 antigen; EGLN_HUMAN; END; Endoglin; Eng; FLJ41744; HHT1; ORW; ORW1; Osler Rendu Weber syndrome 1; RP11 228B15. 2; S endoglin; S-endoglin; SN6
Gene Name
ENG
Gene ID
2022
Swiss Prot
P17813
Reactivity
Human
Immunogen
A synthetic peptide corresponding to the amino acid region 400 - 500 of the human CD105 protein.
Applications
Immunohistochemistry (IHC)
Dilution
It has been optimized for direct use, requiring no further dilution.
Specificity
The antibody can specifically recognize human CD105 protein.
Formulation
The ready - to - use antibody is provided in liquid form in phosphate buffer saline containing stabilizing protein and 0. 05% Proclin 300.
Subcellular Location
Cytoplasmic
Protein Name
CD105
Available Sizes
Frequently Asked Questions
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