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CA 125 (MUC16) Rabbit mAb IHC Kit

Product Specifications

Background

CA125 is a high molecular weight glycoprotein that plays an important role in forming a protective mucous barrier. It is mainly expressed in endometrium, cervical endometrium, fallopian tube epithelial cells and mesothelial cells. However, it is not expressed in normal non menstrual and pregnant ovarie. CA125 is an important marker of ovarian serous adenocarcinoma. It has reference value for the differential diagnosis of serous cystadenocarcinoma and mucinous cystadenocarcinoma. It is mainly used in the study of ovarian cancer and its metastasis.

Synonyms

CA 125; CA-125; CA125; CA125 ovarian cancer antigen; Cancer antigen 125; FLJ14303; MUC 16; MUC-16; MUC16; MUC16_HUMAN; Mucin 16; Mucin 16 cell surface associated; Mucin-16; Mucin16; Ovarian cancer related tumor marker CA125; Ovarian cancer-related tumor marker CA125; Ovarian carcinoma antigen CA125

Gene Name

MUC16

Gene ID

94025

Swiss Prot

Q8WXI7

Reactivity

Human

Immunogen

A synthetic peptide corresponding to the amino acid region External domain of the CA - 125 molecule of the human MUC16 protein.

Applications

Immunohistochemistry (IHC)

Dilution

It has been optimized for direct use, requiring no further dilution.

Specificity

The antibody can specifically recognize human CA-125 protein.

Formulation

The ready - to - use antibody is provided in liquid form in phosphate buffer saline containing stabilizing protein and 0. 05% Proclin 300.

Subcellular Location

Membranous, Cytoplasmic

Protein Name

CA 125

Available Sizes

Frequently Asked Questions

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