Claudin 18 Mouse mAb IHC Kit
Product Specifications
Background
Claudin 18 is a 27kDa membrane protein, belonging to the tight junction protein family. It is highly specifically expressed in gastric epithelial cells, and almost not expressed in other normal tissues. Studies have shown that the expression of gastric tissue increases after cancer, and the abnormal expression in pancreatic cancer, lung cancer, esophageal cancer and ovarian cancer promotes the metastasis of cancer cells. Therefore, antibody based drugs against Claudin 18 can significantly improve the survival rate of patients.
Synonyms
Claudin 18, Claudin-18, CLD18_HUMAN, CLDN18, SFTA5, SFTPJ
Gene Name
CLDN18
Gene ID
51208
Swiss Prot
P56856
Reactivity
Human
Immunogen
A synthetic peptide corresponding to the amino acid region 150 - 261 of the human Claudin 18 protein.
Applications
Immunohistochemistry (IHC)
Dilution
It has been optimized for direct use, requiring no further dilution.
Specificity
The antibody can specifically recognize both human Claudin 18. 1 and Claudin 18. 2 protein.
Formulation
The ready - to - use antibody is provided in liquid form in phosphate buffer saline containing stabilizing protein and 0. 05% Proclin 300.
Subcellular Location
Membranous
Protein Name
Claudin 18
Available Sizes
Frequently Asked Questions
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