Topoisomerase IIα Mouse mAb IHC Kit
Product Specifications
Background
Topoisomerase IIα (Topo IIα) is a nuclear protein with a molecular weight of 170 kDa. It belongs to the topoisomerase family and is expressed in proliferating cells. The main function is to maintain the spatial conformation of DNA and ensure its function. It is mainly used for the study of drug resistance.
Synonyms
Alpha isozyme, ATP hydrolyzing DNA topoisomerase II alfa, DNA gyrase, DNA topoisomerase (ATP hydrolyzing), DNA topoisomerase 2 alpha, DNA topoisomerase 2-alpha, DNA topoisomerase II 170 kD, DNA topoisomerase II alpha isozyme, DNA topoisomerase II, DNA Topoisomerase2, TOP 2A, TOP2, TOP2A, TOP2A_HUMAN, Topoisomerase DNA II alpha 170 kDa, TP2A
Gene Name
TOP2A
Gene ID
7153
Swiss Prot
P11388
Reactivity
Human; Mouse; Rat
Immunogen
A synthetic peptide corresponding to the amino acid region 1400 - 1531 of the human Topoisomerase IIα protein.
Applications
Immunohistochemistry (IHC)
Dilution
It has been optimized for direct use, requiring no further dilution.
Specificity
The antibody can specifically recognize human Topoisomerase IIα protein.
Formulation
The ready - to - use antibody is provided in liquid form in phosphate buffer saline containing stabilizing protein and 0. 05% Proclin 300.
Subcellular Location
Nuclear
Protein Name
Topoisomerase IIα
Available Sizes
Frequently Asked Questions
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