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Progesterone Receptor (PR) Mouse mAb IHC Kit

Product Specifications

Background

There are two isoforms of progesterone receptor, PRA (94kDa) PRB (114kDa), which exist in normal endometrium and breast epithelial cells. Their function is to regulate the expression of genes as transcription factors and affect cytotoxic proliferation and differentiation. A large number of studies show that breast cancer patients with positive ER and PR have good endocrine therapy effect, high remission rate, low recurrence rate and good prognosis. Therefore, PR has been used as a routine examination item for breast cancer patients.

Synonyms

Progesterone receptor, PR, Nuclear receptor subfamily 3 group C member 3

Gene Name

PGR NR3C3

Gene ID

5241

Swiss Prot

P06401

Reactivity

Human

Immunogen

A synthetic peptide corresponding to the amino acid region 200 - 400 of the human Progesterone Receptor protein.

Applications

Immunohistochemistry (IHC)

Dilution

It has been optimized for direct use, requiring no further dilution.

Specificity

The antibody can specifically recognize human Progesterone Receptor protein.

Formulation

The ready - to - use antibody is provided in liquid form in phosphate buffer saline containing stabilizing protein and 0. 05% Proclin 300.

Subcellular Location

Nuclear

Protein Name

Progesterone Receptor

Available Sizes

Frequently Asked Questions

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