PD-1 Mouse mAb IHC Kit
Product Specifications
Background
Programmed death-1 (PD-1) is an important immunosuppressive molecule. It is a member of CD28 superfamily. It is mainly expressed in germinal center related helper T cells and CD8 positive T cells. It includes tyrosine based inhibitory motif immune receptors, and plays an important role in peripheral immune tolerance mechanism and autoimmune diseases. PD-1 is a receptor for PD-L1 and PD-L2. Immune regulation targeting PD-1 is of great significance in anti-tumor, anti infection, anti autoimmune diseases and organ transplantation survival.
Synonyms
CD279, CD279 antigen, hPD 1, hPD l, hPD-1, hSLE1, PD 1, PD-1, PD1, PDCD 1, PDCD1, PDCD1_HUMAN, Programmed cell death 1, Programmed cell death 1 protein, Programmed cell death protein 1, Protein PD 1, Protein PD-1, SLEB2, Systemic lupus erythematosus susceptibility 2
Gene Name
PDCD1
Gene ID
5133
Swiss Prot
Q15116
Reactivity
Human
Immunogen
A synthetic peptide corresponding to the amino acid region 1 - 100 of the human PD - 1 protein.
Applications
Immunohistochemistry (IHC)
Dilution
It has been optimized for direct use, requiring no further dilution.
Specificity
The antibody can specifically recognize human PD-1 protein.
Formulation
The ready - to - use antibody is provided in liquid form in phosphate buffer saline containing stabilizing protein and 0. 05% Proclin 300.
Subcellular Location
Membranous, Cytoplasmic
Protein Name
PD-1
Available Sizes
Frequently Asked Questions
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